Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Features of clonal hematopoiesis associated with greater clinical risk
| Features of higher-risk clonal hematopoiesis |
|---|
| Multiple somatic mutations in myeloid malignancy genes |
| High variant allele frequency (VAF >10%) |
| Variants in TP53 and/or PPM1D |
| DNMT3A R882 variants |
| Hotspot mutation of IDH1 or IDH2 |
