. Author manuscript; available in PMC: 2021 Apr 15.

Published in final edited form as: Cancer. 2020 Jan 22;126(8):1651–1655. doi: 10.1002/cncr.32715

Table 2:

Lifetime breast cancer risk estimates of female relatives of ATM and CHEK2 carriers

				Based on family cancer history and inclusive of the proband’s P/LP variant
				<20%	≥20%
*Relatives of ATM* Carriers**	Based on family cancer history alone	First-degree relatives (N=106)	<20%	46 (43.4%)	36 (34.0%)
		First-degree relatives (N=106)	≥20%	0 (0.0%)	24 (22.6%)
		Second-degree relatives (N=110)	<20%	79 (71.8%)	16 (14.5%)
		Second-degree relatives (N=110)	≥20%	0 (0.0%)	15 (13.6%)
*Relatives of CHEK2* Carriers**	Based on family cancer history alone	First-degree relatives (N=141)	<20%	63 (44.7%)	57 (40.4%)
		First-degree relatives (N=141)	≥20%	0 (0.0%)	21 (14.9%)
		Second-degree relatives (N=101)	<20%	79 (78.2%)	8 (7.9%)
		Second-degree relatives (N=101)	≥20%	0 (0.0%)	14 (13.9%)