TABLE 2.

Predictors of GERD symptoms in past 7 days and GERD as determined by a modified Montreal definition (N=71,812).

Variable	Had GERD symptoms in past 7 days (n=23,039)	OR [95% CI]a		Had GERD symptoms using modified Montreal definition (n=13,881)b	OR [95% CI]a
Age:
18–29 y	6,215 (25.2%)	Reference		3,875 (15.6%)	reference
30–39 y	6,660 (33.7%)	1.34 [1.28–1.40]		4,284 (21.7%)	1.33 [1.25–1.40]
40–49 y	4,364 (35.3%)	1.40 [1.32–1.49]		2,657 (21.4%)	1.26 [1.17–1.34]
50–59 y	3,945 (35.3%)	1.33 [1.25–1.42]		2,180 (19.2%)	1.03 [0.95–1.10]
≥60 y	1,855 (28.9%)	0.98 [0.86–1.11]		885 (13.9%)	0.68 [0.57–0.81]
Gender:
Female	14,575 (33.0%)	reference		8,979 (19.8%)	reference
Male	8,464 (28.7%)	0.88 [0.83–0.93]		4,902 (16.0%)	0.84 [0.79–0.90]
Race/ethnicity:
Non-Hispanic white	17,708 (33.8%)	reference		10,614 (19.4%)	reference
Non-Hispanic black	1,413 (22.6%)	0.62 [0.57–0.69]		860 (13.0%)	0.68 [0.61–0.76]
Latino	2,425 (30.8%)	0.89 [0.79–1.00]		1,569 (19.5%)	1.02 [0.89–1.16]
Asian	805 (19.2%)	0.53 [0.46–0.60]		411 (9.1%)	0.48 [0.41–0.56]
Other	688 (28.2%)	0.81 [0.72–0.92]		427 (17.5%)	0.94 [0.81–1.10]
Education level:
Did not graduate high school	692 (21.1%)	reference		487 (14.6%)	reference
High school graduate	4,906 (31.0%)	1.43 [1.24–1.64]		3,078 (18.8%)	1.16 [1.00–1.35]
Some college	7,526 (33.0%)	1.52 [1.32–1.74]		4,652 (19.2%)	1.15 [1.00–1.33]
College graduate	7,779 (30.9%)	1.33 [1.16–1.53]		4,491 (17.5%)	0.99 [0.85–1.15]
Graduate degree	2,136 (28.5%)	1.20 [1.03–1.41]		1,173 (15.6%)	0.90 [0.74–1.09]
Marital status:
Single	4,619 (23.5%)	reference		2,665 (13.3%)	reference
Divorced, separated, or widowed	2,957 (32.2%)	1.27 [1.14–1.42]		1,828 (18.3%)	1.39 [1.23–1.57]
Married or in long term relationship	15,463 (33.6%)	1.35 [1.28–1.43]		9,388 (19.8%)	1.43 [1.34–1.52]
Employment status:
Unemployedc	8,390 (31.1%)	reference		5,165 (17.6%)	reference
Employed or full-time student	14,649 (30.8%)	1.00 [0.94–1.07]		8,716 (18.2%)	1.02 [0.94–1.11]
Total household income:
$0–50,000	11,535 (30.4%)	reference		7,155 (18.2%)	reference
$50,001–100,000	7,775 (34.5%)	1.12 [1.05–1.19]		4,661 (20.2%)	1.10 [1.02–1.18]
$100,001–200,000	2,498 (32.4%)	1.01 [0.93–1.10]		1,400 (18.1%)	0.95 [0.86–1.05]
≥$200,001	276 (25.3%)	0.81 [0.66–0.99]		162 (14.1%)	0.80 [0.64–0.99]
Prefer not to say	955 (18.6%)	0.57 [0.49–0.68]		503 (8.0%)	0.43 [0.38–0.50]
Irritable bowel syndrome	1,590 (54.7%)	2.19 [1.85–2.59]		1,103 (36.3%)	2.11 [1.76–2.54]
Chronic idiopathic constipation	135 (44.4%)	1.24 [0.78–1.99]		110 (35.0%)	1.66 [0.99–2.79]
Gastrointestinal cancer	123 (28.9%)	0.85 [0.43–1.67]		91 (22.2%)	1.17 [0.49–2.78]
Celiac disease	268 (33.8%)	1.00 [0.82–1.22]		190 (24.2%)	1.11 [0.89–1.39]
Cirrhosis	169 (37.4%)	1.22 [0.89–1.69]		132 (29.4%)	1.60 [1.11–2.31]
Crohn’s disease	232 (42.2%)	1.34 [1.05–1.70]		183 (32.6%)	1.69 [1.31–2.18]
Ulcerative colitis	257 (43.4%)	1.50 [0.89–2.52]		176 (26.3%)	1.34 [0.76–2.36]
Diabetes	1,806 (35.3%)	1.16 [1.04–1.30]		1,139 (20.0%)	1.14 [1.01–1.29]
Endometriosis	808 (44.6%)	1.21 [1.05–1.39]		561 (30.5%)	1.31 [1.13–1.51]
Gallstones	1,536 (48.4%)	1.63 [1.40–1.90]		1,031 (31.1%)	1.63 [1.37–1.94]
HIV/AIDS	67 (28.5%)	0.83 [0.45–1.52]		45 (17.8%)	0.77 [0.32–1.81]
Pancreatitis	270 (44.7%)	1.20 [0.94–1.53]		194 (30.6%)	1.28 [1.00–1.64]
Peptic ulcer disease	743 (57.0%)	2.33 [1.76–3.07]		530 (38.1%)	2.23 [1.79–2.77]
Thyroid disease	1,500 (40.6%)	1.25 [1.10–1.42]		974 (25.0%)	1.31 [1.14–1.49]

Data are presented as n (population-weighted %).

CI, confidence interval; GERD, gastroesophageal reflux disease; OR, odds ratio.

^aThe logistic regression model included all variables listed in the table above.

^bDefined as heartburn or regurgitation occurring ≥2 days in the last week.

^cIncludes those who reported being unemployed, on disability, on leave of absence from work, retired, or homemaker.