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. Author manuscript; available in PMC: 2021 Mar 27.
Published in final edited form as: J Nat Prod. 2019 Oct 2;83(3):569–577. doi: 10.1021/acs.jnatprod.9b00724

Table 5.

In vitro Antiplasmodial Activity of Compounds 12 and 1340

Cmpd P. falciparum
Dd2 (μM)
Cmpd P. falciparum
Dd2 (μM)
1 0.170 ± 0.004 26 >20
1S 0.110 ± 0.007 27 >20
2 0.244 ± 0.005 28 20
13 0.096 ± 0.006 29 >20
14 0.061 ± 0.001 30 >20
15 0.058 ± 0.001 31 19.3 ± 0.6
16 0.067 ± 0.003 32 >20
17 0.060 ± 0.001 33 >20
18 0.077 ± 0.002 34 6.7 ± 0.4
19 0.060 ± 0.001 35 6.3 ± 0.1
20 0.171 ± 0.010 36 >20
21 0.142 ± 0.005 37 8.8 ± 0.3
22 0.058 ± 0.002 38 >20
23 >20 39 5.3 ± 0.1
24 >20 40 >20
25 >20