Table 5.
In vitro Antiplasmodial Activity of Compounds 1 – 2 and 13 – 40
| Cmpd |
P. falciparum Dd2 (μM) |
Cmpd |
P. falciparum Dd2 (μM) |
|---|---|---|---|
| 1 | 0.170 ± 0.004 | 26 | >20 |
| 1S | 0.110 ± 0.007 | 27 | >20 |
| 2 | 0.244 ± 0.005 | 28 | 20 |
| 13 | 0.096 ± 0.006 | 29 | >20 |
| 14 | 0.061 ± 0.001 | 30 | >20 |
| 15 | 0.058 ± 0.001 | 31 | 19.3 ± 0.6 |
| 16 | 0.067 ± 0.003 | 32 | >20 |
| 17 | 0.060 ± 0.001 | 33 | >20 |
| 18 | 0.077 ± 0.002 | 34 | 6.7 ± 0.4 |
| 19 | 0.060 ± 0.001 | 35 | 6.3 ± 0.1 |
| 20 | 0.171 ± 0.010 | 36 | >20 |
| 21 | 0.142 ± 0.005 | 37 | 8.8 ± 0.3 |
| 22 | 0.058 ± 0.002 | 38 | >20 |
| 23 | >20 | 39 | 5.3 ± 0.1 |
| 24 | >20 | 40 | >20 |
| 25 | >20 |