Table 2. Diagnostic efficacy of serum DANCR, CEA and CA199 in differentiating CRC patients from healthy control group.
Molecular marker | Sensitivity | Specificity | Curacy | Positive prediction | Negative prediction |
---|---|---|---|---|---|
(%) | (%) | (%) | (%) | (%) | |
DANCR | 67.5 | 82.5 | 75.0 | 79.4 | 71.7 |
(27/40) | (33/40) | (60/80) | (27/34) | (33/46) | |
CEA | 40.0 | 85.0 | 62.5 | 72.7 | 58.6 |
(16/40) | (34/40) | (50/80) | (16/22) | (34/58) | |
CA199 | 32.5 | 80.0 | 56.2 | 61.9 | 54.2 |
(13/40) | (32/40) | (45/80) | (13/21) | (32/59) | |
DANCR+CEA | 80.0 | 70.0 | 75.0 | 72.7 | 77.7 |
(32/40) | (28/40) | (60/80) | (32/44) | (28/36) | |
DANCR+CA199 | 77.5 | 65.0 | 71.3 | 68.9 | 74.3 |
(31/40) | (26/40) | (57/80) | (31/45) | (26/35) | |
Combined detection of the three markers | 87.5 | 55.0 | 71.3 | 66.0 | 81.5 |
(35/40) | (22/40) | (57/80) | (35/53) | (22/27) |