Table 1. Significant differences in the transcription level of WNTs expression between different types of glioma and normal brain tissue using the ONCOMINE database.
| Database type | Tumor type | P-value | t-test | Fold change | |
|---|---|---|---|---|---|
| WNT5A | Sun brain | Glioblastoma vs. Normal | 3.35 ×10−23 | 12.796 | 2.577 |
| Anaplastic Astrocytoma vs. Normal | 9.86 × 10−7 | 5.963 | 2.250 | ||
| TCGA | Brain Glioblastoma vs. Normal | 2.58 × 10−14 | 24.091 | 4.336 | |
| Lee Brain | Glioblastoma vs. Normal | 1.08 × 10−9 | 24.264 | 14.423 | |
| Bredel Brain 2 | Glioblastoma vs. Normal | 6.70 × 10−8 | 8.799 | 3.768 | |
| French Brain | Anaplastic Oligodendroglioma vs. Normal | 5.16 × 10−7 | 6.287 | 3.127 | |
| WNT7A | Rickman Brain | Astrocytoma vs. Normal | 1.09 × 10−7 | -6.673 | -9.341 |
| WNT10B | Bredel Brain 2 | Glioblastoma vs. Normal | 1.03 × 10−12 | -11.601 | -6.374 |
| Sun Brain | Glioblastoma vs. Normal | 2.49 × 10−27 | -15.662 | -9.563 | |
| Oligodendroglioma vs. Normal | 1.25 × 10−16 | -10.636 | -5.914 | ||
| Diffuse Astrocytoma vs. Normal | 3.97 × 10−5 | -6.781 | -4.025 | ||
| Anaplastic Astrocytoma vs. Normal | 7.94 × 10−8 | -7.364 | -6.300 | ||
| Rickman Brain | Astrocytoma vs. Normal | 3.15 × 10−5 | -7.069 | -2.892 | |
| TCGA Brain | Brain Glioblastoma vs. Normal | 1.86 × 10−9 | -20.916 | -7.016 |
Differences in transcriptional expression were compared by Students’ t-test. Cut-off of P-value and fold-change were as follows: P-value: 0.01, fold-change: 1.5, gene rank: 10%.