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. 2020 Jan 17;9(4):531–542. doi: 10.1002/sctm.19-0199

Figure 3.

Figure 3

The combination of valproic acid (VPA) and cytokines drives ex vivo expansion of phenotypically defined hematopoietic stem cells (HSCs). A,B, Percentage of mobilized peripheral blood (mPB)‐CD34+ (A) and CD34+CD45RA‐CD90+ (B) cells throughout 7 days of culture in the presence of either cytokines alone or cytokines and VPA (mean ± SD, n = 16). C,D, Absolute numbers of mPB‐CD34+ (C) and CD34+CD45RA‐CD90+ (D) cells throughout 7 days of culture (mean ± SEM, n = 16). E, Summary of the fold expansion of phenotypically defined HSC populations from both mPB (n = 16) and adult bone marrow (ABM; n = 9) cultures, on day 7 (mean ± SEM). *P < .05; **P < .01; ***P < .001