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. 2020 Mar 20;11:408. doi: 10.3389/fimmu.2020.00408

Figure 5.

Figure 5

tRA-induced microbiota changes in pristane-induced lupus. (A) Quantitation of the relative abundance of the order Lactobacillales and genus Lactobacillus at 2 weeks following lupus induction as determined with 16S rRNA sequencing. (B) Relative abundance of Bacteroidales at the same time point. (C) Serum endotoxin levels at the same time point. (D) Expression of tight junction transcript Occludin in the IECs at 6 months post pristane injection. (E) Relative abundance of the phyla Bacteroidetes and Firmicutes at 22 weeks post lupus induction. (F) Correlation between the relative abundance of Bacteroidetes and glomerular pathological scores. Significant differences were shown as *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.