Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 23;14(7):827–843. doi: 10.1586/14737159.2014.940319

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Informa UK, Ltd.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Figure 2. — Helicase-dependent amplification. (A) Helicase unwinds the dsDNA. (B) SSB protein prevents premature strand reassociation. (C) Primer hybridizes with the target and is extended by the DNA polymerase while helicase continues unwinding the dsDNA remaining. (D) New dsDNA copy is formed as a product and is able to go into to a new cycle.