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. 2013 Oct 3;17(12):1439–1460. doi: 10.1517/14728222.2013.837886

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Figure 1. — CCL5 biology. The chemokine receptors for CCL5 and common shared agonists for these receptors are illustrated. Chemokine receptor activation has major effects on leukocyte and nonleukocyte populations. Such biological effects may be modulated by the action of nonfunctional (CCR5Δ32) or decoy receptors (D6 and DARC), by chemokine receptor homo- and heterodimerization, or by a combination of both.