TABLE 7.

Recommendations for HP eradication

1) Bismuth quadruple therapy (PPI + Bismuth + Two antibiotics)*
2) Bismuth-out quadruple therapy (PPI + Three antibiotics)
3) High dose PPI (4X1) + Amoxicillin 500 mg (4x1) + Tetracycline 500 mg (3 x 1) + Metronidazole 500 mg (3 x 1)
First-line therapy:	Bismuth containing quadruple therapy	OR Sequential treatment without bismuth
	Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1	7 days;
	Colloidal bismuth subcitrate 300 mg tb 4x1	Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
	Tetracycline 500 mg tb 4x1	Amoxicillin 750 mg tb 3x1,
	Metronidazole 500 mg tb 3x1	7 days;
		Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
		Tetracycline 500 mg tb 4x1
		Metronidazole 500 mg tb 3x1
Second-line therapy:	Concomitant (without bismuth) quadruple therapy:	OR Hybrid therapy:
	Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1	7 days;
	Amoxicillin 750 mg tb 3x1	Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
	Metronidazole 500 mg tb 3x1	Amoxicillin 750 mg tb 3x1
	Clarithromycin 500 mg tb 2x1	7 days;
		Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
		Amoxicillin 750 mg tb 3x1
		Clarithromycin 500 mg tb 2x1
		Metronidazole 500 mg tb 3x1
Third-line therapy	Levofloxacin Bismuth containing quadruple therapy:	OR Sequential treatment with levofloxacin:
	Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1	7 days;
	Colloidal bismuth subcitrate 300 mg tb 4x1	Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
	Amoxicillin 750 mg tb 3x1	Amoxicillin 750 mg tb 3x1
	Levofloxacin 500 mg tb 2x1	7 days;
		Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
		Amoxicillin 750 mg tb 3x1
		Levofloxacin 500 mg tb 2x1
Fourth-line therapy	Culture + Treatment should be arranged according to antibiogram result	OR 14 days;
		Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
		Amoxicillin 750 mg tb 3x1
		Rifabutin 150 mg tb 2x1
		OR 7 days;
		Esomeprazole 40 mg or rabeprazole 20 mg tb 3x1
		Colloidal bismuth subcitrate 300 mg tb 4x1
		Tetracycline 500 mg tb 4x1
		Furazolidone 200 mg tb 2x1