Table 4.
Multivariable Cox regression analyses for overall survival (OS) and disease free survival (DFS) based on the model with DW-MRI and 18F-FDG PET/CT parameters and histology.
| Predictors | Hazard ratio (95% CI) | |
|---|---|---|
| Overall survival* | ΔADCduring (%) | 0.98 (0.95 – 1.01) |
| ΔSUVmean,post (%) | 0.99 (0.97 – 1.01) | |
| Squamous cell carcinoma† | 0.67 (0.21 – 2.16) | |
| Disease free survival§ | ΔADCduring (%) | 0.98 (0.95 – 1.01) |
| ΔSUVmean,post (%) | 1.00 (0.98 – 1.01) | |
| Squamous cell carcinoma† | 0.65 (0.17 – 2.44) |
Analyses based on 63 patients of whom 27 deceased during follow-up. The applied exclusion criteria were no post-treatment 18F-FDG PET/CT available (n=3), no uptake on post-treatment 18F-FDG PET/CT (n=1), histology other than adenocarcinoma or squamous cell carcinoma (n=1) and incomplete follow-up data (n=1).
Analyses based on 57 patients of whom 24 had disease recurrence during follow-up. The applied exclusion criteria were no post-treatment 18F-FDG PET/CT available (n=3), no uptake on post-treatment 18F-FDG PET/CT (n=1), histology other than adenocarcinoma or squamous cell carcinoma (n=1), incomplete follow-up data (n=5) and censored before earliest event (n=1).
Adenocarcinoma was used as reference category.
ADC apparent diffusion coefficient; CI confidence interval; SUV standardized uptake value; TLG tumor lesion glycolysis; TRG tumor regression grade