Fig. 3.

Limit of detection of ADA against bnAbs PGT121, 3BNC117, 10–1074, and PGDM1400. Anti-idiotype antibodies specific for each bnAb were diluted in PBS at seven different concentrations prior to titrating in the assay. Data are graphed as the percent neutralizing activity of the bnAb at each dilution of ADA. Percent inhibition of virus infectivity by each bnAb in the absence of anti-idiotype antibody is indicated above the corresponding figure.