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. 2020 Mar 19;180(6):1245–1261.e21. doi: 10.1016/j.cell.2020.02.009

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© 2020 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Figure S4 — K1268 Ubiquitylation Prevents Short Genes from Escaping the UV-Induced Transcription Shutdown, Related to Figure 4

(A) Browser tracks of the TT_chem-seq experiment, showing a long (PTEN), a medium (TIMP3) and two short genes (RGS16 and FOSB), before and 45 min or 3 h after UV irradiation. The data are normalized to yeast spike-in.

(B) Scatter-density plots showing the genes that are differentially expressed between K₁₂₆₈R and WT cells (TT_chem-seq data) stratified by gene length, at different times after UV irradiation (20 J/m²). Each gene is represented by one dot. Plots are colored by binned spot density from low (blue) to high (red).