Table 3.
Interpretive Criteria for Reporting MLH1 Promoter Hypermethylation Status
Analytical result | Clinical interpretation |
---|---|
β Values for all four MLH1 CpG sites greater than or equal to their respective cutoffs | MLH1 promoter hypermethylation positive |
β Values of less than four of the MLH1 CpG greater than or equal to their respective cutoffs | MLH1 promoter hypermethylation negative |
CpG, cytosine-guanine dinucleotide.