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. 2020 Mar 26;8(6):1065–1073. doi: 10.12998/wjcc.v8.i6.1065

Table 2.

Response to treatment with ruxolitinib

Parameter aGVHD, n = 10 cGVHD, n = 28
Overall response rate, n (%) 10 (100) 22 (82.1)
Median follow-up time in mo, median (range) 2.5 (1.5–4) 5 (1.5–10)
Time to best overall response in mo, median (range) 1.0 (0.5–2.5) 3.0 (1.0–9.5)
Time to best response for each organ system in d, median (range)
Skin 28 (14–28) 77 (7–147)
Digestive tract 25 (14–60) 259 (70–308)
Liver 32 (21–42) 42 (28–56)
Eye - 112 (42–182)
Oral cavity - 80 (28–168)
Lung - 91 (49–140)
Fascia - 91 (56–266)
Discontinuation of immunosuppressive agents after ruxolitinib, n (%) 8 (80.0) 21 (75.0)

aGVHD: Acute graft-vs-host disease; cGVHD: Chronic graft-vs-host disease.