Table 2.

Grouping of WT mice for various lab and experimental procedures.

Lab/behavioral investigation		Behavior evaluation (OF/NOR/MWM)	EEG recording	Nav expression analysis (Western blotting/cell-surface biotinylation assay)
Grouping of WT mice		Number of mice
Early 12-week WT control	2 m	11	5	11
	3.5 m	11	5	11
	5 m	11	5	11
Late 12-week WT control	6.5 m	11	5	11
	8 m	11	5	11
	9.5 m	11	5	11
24-week WT control	2 m	11	5	11
	3.5 m	11	5	11
	5 m	11	5	11

2 m, 2-month-old; 3.5 m, 3.5-month-old; 5 m, 5-month-old; 6.5 m, 6.5-month-old; 8 m, 8-month-old; 9.5 m, 9.5-month-old. The age of the mice in the table corresponds to the age at the beginning of the study. The mice in the early 12-week WT control groups survived for 12 weeks and were used for behavior evaluation and then sacrificed for the Nav protein analysis, as in the other groups. OF; open field; NOR: novel object recognition task; MWM: Morris water maze test; EEG: electroencephalogram.