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. 2019 Nov 25;63(6):2789–2801. doi: 10.1021/acs.jmedchem.9b01518

Table 11. Pharmacokinetic Parameters of 20, Cefepime, and AVI in Mice Following Intravenous Administration.

entry t1/2 (h) AUCinf (h·ng/mL) Vss (mL/kg) CL (mL/h/kg)
20 0.16 16 189 143 618
cefepime 0.39 15 800 330 648
AVI 0.1 8075 210 1238