Table 11. Pharmacokinetic Parameters of 20, Cefepime, and AVI in Mice Following Intravenous Administration.
entry | t1/2 (h) | AUCinf (h·ng/mL) | Vss (mL/kg) | CL (mL/h/kg) |
---|---|---|---|---|
20 | 0.16 | 16 189 | 143 | 618 |
cefepime | 0.39 | 15 800 | 330 | 648 |
AVI | 0.1 | 8075 | 210 | 1238 |