Table 7. MICs against Selected Gram-Negative Pathogens for Meropenem (MEM) and Meropenem Plus 20.
| MIC with meropenem fixed at 4 μg/mL (μg/mL) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| species | strain ID | β-lactamase content | MEM MIC (μg/mL) | 20 | 17 | 1 | 3 | VAB | TZB | AVI |
| K. pneumoniae | ATCC BAA 1705 | KPC-2 | 16 | 0.015 | 0.015 | 0.0079 | 0.0079 | 0.03 | 8 | 0.015 |
| K. pneumoniae | CDC-0040 | VIM-27, CTX-M-15, SHV-11, OXA-1 | >128 | 8 | >16 | >16 | >16 | >16 | >16 | >16 |
| E. coli | CDC-0055 | NDM-1, CMY-6, OXA-1 | 32 | 0.25 | 8 | 16 | 1 | >16 | >16 | 8 |
| K. pneumoniae | CDC-0066 | OXA-232, OXA-9, TEM-1A, CTX-M-15, OXA-1 | 32 | 4 | 8 | 2 | 4 | >16 | >16 | 2 |
| P. aeruginosa | CDC-0356 | KPC-2, PDC-42 | 32 | 1 | 4 | 2 | 1 | 8 | >16 | 0.5 |
| K. pneumoniae | CDC-0361 | KPC-2, SHV-12, TEM-1 | 16 | 0.015 | 0.015 | 0.0079 | 0.0079 | 0.06 | >16 | 0.015 |
| E. coli | CDC-0452 | NDM | 32 | 0.25 | 8 | 8 | 2 | >16 | >16 | 8 |
| P. aeruginosa | CDC-0457 | VIM | 128 | >16 | >16 | >16 | >16 | >16 | >16 | >16 |