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. Author manuscript; available in PMC: 2020 Aug 24.
Published in final edited form as: Nat Med. 2020 Feb 24;26(3):354–359. doi: 10.1038/s41591-020-0763-1

Fig. 1. Retinal sensitivity following gene therapy for X-linked retinitis pigmentosa in cohort 3 patients.

Fig. 1

Mean retinal sensitivity (decibels, dB) and visual field, (represented by sensitivity heat maps) measured by microperimetry, showed progressive improvement in the treated eye from baseline to 6 months post-treatment. The untreated eye showed no change. Visual acuity, measured by ETDRS chart reading (number of letters), remained stable in both eyes. To minimize learning effects, baseline microperimetry was conducted in triplicate over a 2-day period at visit 1 for all subjects. The third reading was validated as an accurate baseline. At follow-up visits, assessments were conducted once for each eye, as per trial protocol.