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. Author manuscript; available in PMC: 2020 Mar 30.
Published in final edited form as: Alcohol Clin Exp Res. 2018 May 27;42(7):1206–1216. doi: 10.1111/acer.13765

Fig. 1.

Fig. 1.

Serum n-acetyl cysteine (NAC) concentrations and 4-point bend testing in ethanol (EtOH)-fed rats following treatment with NAC. EtOH-fed rats were injected with NAC at 200, 400, and 800 mg/kg body weight (b.w.) for 3 days. Serum and femur bones were collected and tested for (A) serum NAC concentrations determined by HPLC following 3 or 21 days of injections. (B) Four-point bend testing on femurs following EtOH and NAC administration. Significantly different compare to EtOH alone NAC 200 (***p < 0.001), NAC 400 (**p < 0.002), and NAC 800 (*p < 0.03), respectively. N = 6 for control and EtOH-fed rats. N = 3 for 200, 400, and 800 mg/kg b.w. NAC-treated EtOH-fed rats.