Table 1.

Results from systematic reviews

Mortality	RR	95% CI	NNT	95% CI
Multiple doses	0.63	0.39–1.02	14	7–1000
Natural surfactant	0.86	0.76–0.98	50	20–1000
Prophylaxis	0.61	0.48–0.77	20	14–50
Early	0.87	0.77–0.99	33	17–1000
Early INSURE	0.38	0.08–1.81	—	—

Abbreviation: NNT, numbers needed to treat.

Data published in the Cochrane Database of Systematic Reviews.^{19, 20, 21, 22, 23, 24, 25, 26}