Bohnhorst 2010.

Methods	Randomised cross‐over trial
Participants	35 infants of gestational age < 32 weeks with a history of apnoea and desaturation (> 3 episodes of oxygen saturation ≤ 80% in 6 hours) or bradycardia (> 3 episodes of heart rate ≤ 80 beats per minute in 6 hours) participated 32 out of 35 infants completed the study
Interventions	Nasal vs oral placement of enteral feeding tube (5 Fr gauge) for 2 sequential 12‐hour periods
Outcomes	Oxygen saturation measured with pulse oximetry; episodes of apnoea and bradycardia
Notes	Setting: Department of Neonatology, Hannover Medical School, Germany (2008‐2009)
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation	Low risk	Computer‐generated
Allocation concealment	Unclear risk	Method not stated
Blinding All outcomes	High risk	Caregivers not blinded, but respiratory monitoring assessed by investigator unaware of infant's identity or feeding tube route sequence
Incomplete outcome data addressed All outcomes	Low risk	Near‐complete follow‐up (32 out of 35 infants completed study)