Fig. 3.

Patients with stable LN have higher numbers of circulating CD117⁺ ILCs and cytokine-producing ILCs. a Differences in clinical parameters of those with active and stable LN. b Changes in total ILCs, CD117⁺ ILCs, CRTH2⁺ ILCs, and CD117⁻/CRTH2⁻ ILCs are shown as min. to max. Box-and-whisker plots (line represents the median). c, d Changes in IFN-γ⁺, IL-13⁺, IL-17A⁺, PD-1⁺ ILCs, and cytokine-negative ILCs in PBMC from those with active LN (n = 12) or stable LN (n = 10). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 (Student’s t test). ^##P < 0.01 (Mann-Whitney test)