Table 1.
Baseline characteristics. Data are median (25th/75th centiles) or n (%). Bold type indicates significant p value.
| Variable | Intervention | Placebo | p value |
|---|---|---|---|
| Age (years) | 4.9(4.4,5.2) | 5.1(4.5,5.4) | 0.318 |
| Gender (female) | 7(58%) | 8(42%) | 0.295 |
| Ethnicity (caucasian) | 12(100%) | 14(74%) | 0.21 |
| Height (cms) | 107.5(102.5, 113.4) | 108.1 (103.8, 114) | 0.43 |
| Weight (kg) | 18.3 (16.9, 21.7) | 17.8 (16.2, 18.8) | 0.68 |
| BMI (kg/m2) | 16.1 (15.7, 17.0) | 15.0 (14.1, 16.2) | 0.16 |
| Serum 25OHD (nmol/l) | 71(58,98) | 79(61,81) | 0.537 |
| Serum calcium (mmol/l) | 2.4(2.37,2.42) | 2.35(2.31,2.42) | 0.615 |
| Serum phosphate (mmol/l) | 1.52(1.5,1.62) | 1.61(1.55,1.69) | 0.058 |
| Serum alkaline Phosphatase (u/l) | 204.5(180,215) | 200(186,213) | 0.864 |
| Serum albumin (g/l) | 42(41,44) | 42(41.5,43.5) | 0.634 |
| Serum magnesium (mmol/l) | 0.85(0.85,0.89) | 0.84(0.82,0.88) | 0.379 |
| Serum parathyroid hormone (ng/l) | 27.9(24.0,34.1) | 36.5(22.3,40.0) | 0.685 |
| Serum P1NP (ng/ml) | 552.2(512.3,678.6) | 587.1(518.2,801.7) | 0.558 |
| Serum CTX (ng/ml) | 1.52(1.3,1.81) | 1.59(1.3,1.81) | 0.618 |
| Dietary calcium intake (gms/day) | 783(577,842) | 521(430,535) | 0.040 |
| Activity score (METS units) | 66 (44,83) | 104 (68,120) | 0.040 |