Table 2.
Comparison of bone turnover markers at baseline and post vibration by randomisation group. Data are median (25th/75th centiles) or n (%). Bold type indicates significant p value.
| Variable | Intervention | Placebo | Between group difference (95% confidence interval) | P value |
|---|---|---|---|---|
| Median serum P1NP (ng/ml) at baseline | 552.2(512.3,678.6) | 587.1(518.2,801.7) | - | 0.558 |
| Mean change in P1NP (ng/ml) between baseline and D8 | 40.6 | -92.6 | 133.2 (0.4, 266.0) | 0.049 |
| Mean % change in P1NP between baseline and D8 | 11 | -13.3 | 24 | - |
| Median serum CTX (ng/ml) at baseline | 1.52(1.3,1.8) | 1.59(1.3,1.8) | - | 0.618 |
| Mean change in CTX (ng/ml) between baseline and D8 | -0.034 | -0.084 | 0.05 (-0.159,0.26) | 0.620 |
| Mean % change in CTX between baseline and D8 | -0.5 | -4.9 | 4.4 | - |