Summary of reported prevalence of clonal hematopoiesis. The bar graphs represent the total number of individuals with clonal hematopoiesis associated with (magenta) and without (gray) known driver gene mutations reported in three independent studies (13, 15, 31). The donuts summarize the frequencies of somatic mutations in candidate driver genes; the numbers within the donuts indicate the total number of driver gene mutations detected. Abbreviations: CH-CD, clonal hematopoiesis with candidate driver mutations; CH-UD, clonal hematopoiesis with unknown driver mutations; SNV, single nucleotide variant; VAF, variant allele frequency.