Table 2.
Cognition, HRQOL and social attainment
| Survivors | Controls | FDR-P vs. norms | FDR-P vs. control | |||
|---|---|---|---|---|---|---|
| M (SD) | %Imp | M (SD) | %Imp | |||
| Global Cognition | ||||||
| Verbal reasoning | −0.45(1.15) | 25.5% | 0.19(0.9) | 6.6% | <0.001 | <0.001 |
| Non-verbal reasoning | 0.06(0.88) | 10.1% | 0.27(0.73) | 3.7% | 0.48 | 0.065 |
| Academics | ||||||
| Reading | −0.37(0.66) | 8.8% | 0(0.54) | 1.7% | <0.001 | <0.001 |
| Mathematics | −0.63(1.07) | 25.0% | −0.12(0.81) | 7.8% | <0.001 | <0.001 |
| Attention | ||||||
| Sustained attention: omissions | −0.23(1.52) | 14.5% | 0.14(1.11) | 7.2% | 0.101 | 0.011 |
| Sustained attention: variability | −0.35(1.28) | 19.3% | −0.03(1.1) | 11.3% | 0.0034 | 0.017 |
| Focused attention | 0.01(1.23) | 12.1% | 0.58(0.83) | 2.9% | 0.98 | <0.001 |
| Processing speed | ||||||
| Visuomotor | −0.15(1.03) | 16.8% | 0.45(0.94) | 3.7% | 0.101 | <0.001 |
| Cognitive | 0.22(1.14) | 12.5% | 0.64(0.91) | 1.4% | 0.050 | 0.0011 |
| Memory | ||||||
| Memory span | 0(1) | 5.3% | 0.15(0.94) | 4.6% | 0.98 | 0.15 |
| Verbal learning | −0.18(1.04) | 18.4% | 0.35(1) | 7.5% | 0.048 | <0.001 |
| Long-term verbal memory | −0.37(1.14) | 20.0% | 0.11(1.03) | 9.2% | <0.001 | <0.001 |
| Visual memory | −0.45(1.13) | 30.1% | −0.06(0.97) | 11.8% | <0.001 | 0.0015 |
| Executive function | ||||||
| Working memory | −0.23(0.98) | 7.3% | 0.02(0.86) | 2.3% | 0.0092 | 0.0096 |
| Self-monitoring | −0.28(1.37) | 20.0% | −0.12(1.48) | 12.7% | 0.025 | 0.43 |
| Cognitive flexibility | −0.52(1.73) | 23.0% | 0.3(1.18) | 7.5% | <0.001 | <0.001 |
| Initiation | −0.21(1.04) | 18.8% | 0.08(1.08) | 13.0% | 0.025 | 0.0071 |
| Health Related Quality of Life SF-36 | ||||||
| Physical function | −0.16(1.1) | 20.6% | 0.39(0.7) | 4.7% | 0.097 | <0.001 |
| Role limitations physical problems | −0.26(1.22) | 27.7% | 0.43(0.67) | 6.0% | 0.022 | <0.001 |
| Bodily pain | −0.22(1.22) | 27.0% | 0.41(0.91) | 8.9% | 0.047 | <0.001 |
| General health | −0.56(1.2) | 36.4% | 0.26(0.91) | 7.4% | <0.001 | <0.001 |
| Vitality | −0.2(1.15) | 24.1% | 0.15(0.97) | 14.5% | 0.052 | <0.001 |
| Social functioning | −0.34(1.14) | 22.0% | 0.18(0.86) | 8.6% | 0.0018 | <0.001 |
| Role limitations emotional problems | −0.29(1.31) | 22.1% | 0.22(0.79) | 9.0% | 0.018 | <0.001 |
| Mental health | −0.28(1.24) | 24.8% | 0.07(0.92) | 15.0% | 0.018 | 0.0002 |
| Social attainment | N (%) | N (%) | ||||
| Education: college graduate or more | 46 (30.7) | 190 (54.6) | <0.001 | |||
| Employment: full time | 84 (59.6) | 248 (74.0) | 0.0026 | |||
| Marital status: ever married | 97 (69.3) | 267 (79.5) | 0.091 | |||
| Household income: ≥$ 40 000 | 56 (49.1) | 249 (79.0) | <0.001 | |||
| Independent living | 95 (68.3) | 294 (87.0) | <0.001 | |||
| Health insurance | 108 (75.5) | 294 (87.5) | 0.013 | |||
Z-scores, M=0, SD=1, higher score indicates better outcome. %Imp = percent of the group falling in the impaired range, defined as a score in the bottom 10th percentile of the normal distribution. Comparisons between survivors and controls were adjusted for difference in race, sex and age. Multiple comparisons between survivors and controls and survivors and population norms were adjusted using false discovery rates (FDR).