for the main comparison.

Educational training programme to prevent wrong‐site tooth extraction
Patient or population: Dental patients requiring tooth extraction Settings: Outpatient department of a university hospital, Taiwan Intervention: Educational training programme (Professional intervention) Comparison: Not applicable
Outcomes	Change in level/slope	No of studies (no of extractions)	Quality of the evidence (GRADE)	Comments
Annual incidence rates of wrong‐site tooth extraction	Change in level: ‐4.52%; 95% CI ‐6.83% to ‐2.21%; SE 0.53; P < 0.05   Change in slope: ‐1.16; 95% CI ‐2.22 to ‐0.10; SE 0.24; P < 0.05	1 ITS study (24,406 tooth extractions before intervention; 28,084 after intervention)	Low1	Data re‐analysed
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate Very low quality: We are very uncertain about the estimate

1. Quality of the evidence: findings of the included study were from a single institution and were specific to the individual patient population. Therefore, the generalisability and applicability of the results was questionable with the need for caution to be exercised in applying the results to other settings. This research provides some indication of the likely effect. However, the likelihood that it will be substantially different is high.
 
 CI: confidence interval; ITS: interrupted time series; SE: standard error.