Figure 3.

Specc1l^cGT/ΔC510 compound mutants show transient oral adhesions. (A–F) Coronal H&E palate sections of WT and Specc1l^cGT/ΔC510 mutant embryos at E13.5. Compound mutants show evidence of adhesions between the oral and nasal cavity epithelia (A vs. B; arrows) and between the oral and tongue epithelia (C vs. D; arrows). Adhesions were also identified at the junction between the tongue and palatal shelf (E vs. F; arrows), which resulted in separation of the palatal shelf epithelium from the mesenchyme (F′; arrows). Scale bars are 50 μm.