NO was elevated in BAEC after 36 h in the laminar but not
disturbed flow parallel plate flow chamber. (a,
top) BAEC confocal microscopy images (20×) in varied flow
regimes for 36 h showing NO (DAF-FM, green) and nuclei
(bisbenzimide, blue). (a, bottom) NO only (DAF-FM,
green) confocal microscopy images (20×).
(b, left) DAF signal after thresholding to remove
noise. (b, right) Total DAF-FM fluorescence
intensity quantification for BAEC exposed to static or flow
conditions for 36 h (122 images among 18 samples, across 4
independent experiments). *** indicates
p < 0.0001 (LFG
compared to all other conditions).