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. Author manuscript; available in PMC: 2021 Mar 3.
Published in final edited form as: Cell Metab. 2020 Feb 6;31(3):580–591.e5. doi: 10.1016/j.cmet.2020.01.009

Figure 7. NLRP3 Deacetylation Improves Aging-associated Glucose Homeostasis in vivo.

Figure 7.

Hematopoietic stem cells from aged WT mice were transduced with WT or K21/22/24R mutant NLRP3 and transplanted into lethally irradiated aged WT mice to reconstitute their hematopoietic system. Mice were analyzed 6 weeks post-transplantation for glucose tolerance tests (A, B), plasma IL-18 (C), and body weight (D). Error bars represent SE. *: p<0.05. n.s.: p>0.05. Student’s t test.