Table 1.

Summary of sample sizes of statistically tested groups

I. Metric	II. Experimental groups	III. Condition	IV. Compiled number of nuclei	V. Number of coverslips	VI. Number of individuals	VII. Test and sample size used
Density	Patients	Static	14,629	95	9	ANOVA coverslips (column V)
		Stretch	15,065	102
	Negative Controls	Static	17,492	112	10
	Stretch	16,450	118
	Positive Controls	Static	5789	46	1
Stretch	5751	46
Actin OOP	Patients	Static	N/A	94	9	ANOVA coverslips (column V)
		Stretch	101
	Negative Controls	Static	N/A	112	10
	Stretch	117
	Positive Controls	Static	N/A	47	1
Stretch	47
Fibronectin OOP	Patients	Static	N/A	81	9	ANOVA coverslips (column V)
		Stretch	88
	Negative Controls	Static	N/A	102	10
	Stretch	107
	Positive Controls	Static	N/A	41	1
Stretch	41
% Defective nuclei	Patients	Static	5823	94	9	Kruskal–Wallis and Dunn's multiple comparison coverslips (column V)
		Stretch	5832	102
	Negative Controls	Static	7687	112	10
	Stretch	7595	117
	Positive Controls	Static	3059	46	1
Stretch	2921	46
Aspect ratio and area	Patients A	Static	738	33	3	ANOVA nuclei (column IV) and individuals (column VI)
		Stretch	1012	40
	Patients B	Static	2445	30	3
		Stretch	2480	30
	Patients C	Static	2640	31	3
		Stretch	2340	32
	Negative Controls	Static	7687	112	10
	Stretch	7595	117
	Positive Controls	Static	3059	46	1
Stretch	2921	46