. Author manuscript; available in PMC: 2020 Mar 30.

Published in final edited form as: Biomed Pharmacother. 2019 Aug 7;118:109323. doi: 10.1016/j.biopha.2019.109323

Table 1.

Physicochemical characterization of SpHL, SpHL-Fol, SpHL-DOX, and SpHL-DOX-Fol.

	Size (nm)	Polydispersity Index (PDI)	Zeta Potential (mV)	Encapsulation Percentage (%)
SpHL	126 ± 4	0.09 ± 0.03	−3.7 ± 1.3	–
SpHL-Fol	130 ± 7	0.07 ± 0.03	−5.0 ± 1.2	–
SpHL-DOX	123 ± 6	0.07 ± 0.01	−3.3 ± 0.7	100.9 ± 1.8
SpHL-DOX-Fol	129 ± 5	0.06 ± 0.03	−4.2 ± 1.4	97.6 ± 3.8

Data are expressed by the mean (n = 3) ± standard deviation of the mean. All data were analyzed by one-way ANOVA analysis of variance followed by Tukey’s post-test.