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. Author manuscript; available in PMC: 2020 Mar 30.
Published in final edited form as: Biomed Pharmacother. 2019 Aug 7;118:109323. doi: 10.1016/j.biopha.2019.109323

Table 2.

Release profile of SpHL-DOX-Fol at pH 7.4 and pH 5.0 at different times.

pH 7.4 pH 5.0
Time 1 h 4 h 24 h 1 h 4 h 24 h
Release (%) 11.0 ± 1.7 22.4 ± 3.2a 21.5 ± 3.9a 11.6 ± 2.9 42.3 ± 7.9ab 53.6 ± 5.7 ab
a

Represents statistical differences (P < 0.05) between 1 h and 4 h or 24 h at the same pH.

b

Represents statistical differences (P < 0.05) between pH 7.4 and pH 5.0 at the same time.

Data are expressed by the mean (n = 3) ± standard deviation of the mean. All data were analyzed by one-way ANOVA analysis of variance followed by Tukey’s post-test.