Fig. 1.

Survivors of K. pneumoniae (Kp) respiratory tract inoculation are protected upon subsequent Kp challenge. (A) Schematic of experimental course in which C57BL/6J mice are intratracheally inoculated with Kp or PBS followed by challenge with Kp 28 days later. (B) Survival of mice inoculated with Kp or PBS over 28 days (left; Kp n=40, PBS n=20) and over 14 days after challenge with Kp (right; Kp/Kp n=15, PBS/Kp n=20). (C) Daily weights of mice inoculated with Kp or PBS over 28 days (left) and over 14 days after challenge with Kp (right) are presented as a percentage of weight at day 0 inoculation (left) or day 0 challenge (right). Data are shown as mean±s.e.m. and are combined from at least three independent experiments. *P<0.05, **P<0.01; Mantel–Cox log-rank test.