Table 2.
List of various classes of compounds and their pharmacological activities reported in Cordyceps sinensis.
| Constituents | Pharmacological functions | References | |
|---|---|---|---|
| Polysaccharides | |||
| – | Antioxidant activity | Li et al., 2001a, Yu et al., 2006a, Yu et al., 2006b and Zhang et al. (2011) | |
| CS-F30 and CS-F10 | Hypoglycemic and hypolipidemic effect | Kiho, Ookubo, Usui, Ukai, and Hirano (1999), Kiho et al. (1996) | |
| Polysaccharide fraction from CS (PSCS) | Antileukemic | Chen et al. (1997) | |
| Mannoglucan | Cytotoxic activity | Wu et al. (2007b) | |
| Exo-polysaccharides | Immunomodulatory and antitumour effects | Yang et al., 2005, Zhang et al., 2005 and Zhang, Li, Qiu, Chen, and Zheng (2008) | |
| Acid polysaccharide fraction (APSF) | Immunomodulatory effect | Chen, Zhang, Wenbin Shen, and Wang (2010) and Chen et al. (2012) | |
| Heteropolysaccharides (PS-A) | Hypercholestrolemia | Kim (2010) | |
| Nucleosides | |||
| Adenosine | Immunomodulatory & pharmacokinetic effects, cardioprotection | Kim (2010) and Yu, Zhao, Zhu, and Li (2007) | |
| Guanosine | Immunomodulatory effects | Kim (2010) | |
| Cordycepin | Anti-cancer effects, pharmacokinetic effect, immunomodulatory effect, antileukemic | Kodama et al., 2000, Nakamura et al., 2006, Pao et al., 2012, Tsai et al., 2010,Yoshikawa et al. (2011) and Zhou et al. (2008) | |
| Sterols | |||
| Ergosterol | Anti-cancer effects | Matsuda et al. (2009) and Wu et al. (2007a) | |
| β-Sitosterol | Anti-cancer effects | Matsuda et al. (2009) and Wu et al. (2007a) | |
| 5a,8a-Epidioxy-24(R)-methylcholesta-6,22-dien-3b-d-glucopyranoside | Anti-cancer effects | Bok et al. (1999) | |
| 5,6-Epoxy-24(R)-methylcholesta-7,22-dien-3b-ol | Anti-cancer effects | Bok et al. (1999) | |
| 5α,8α-Epidioxy-22E-ergosta-6,22-dien-3β-ol | Anti-cancer effects | Matsuda et al. (2009) | |
| 5α,8α-Epidioxy-22E-ergosta-6,9(11),22-trien-3β-ol | Anti-cancer effects | Matsuda et al. (2009) | |
| 5α,6α-Epoxy-5-ergosta-7,22-dien-3β-ol | Anti-cancer effects | Matsuda et al. (2009) | |
| Protein constituents | Hypotensive and vasorelaxant activities | Chiou et al. (2000) | |
| Proteins | |||
| CSAP | Anti-bacterial activity | Zheng et al. (2006) | |
| Cordymin (peptide) | Anti-inflammatory and anti-nociceptive activities | Qian et al. (2012) | |
| Cordycedipeptide A (cyclodipeptide) | Cytotoxic activities | Jing et al. (2005) | |
| Cordyceamides A and B | Cytotoxic activities | Jia et al. (2009) | |