Table 1.
Matrix of the simple centroid mixture design and experiment data of extraction yield, NO production and IL-6 production.
| Run | Independent variablesa |
Response variablesb |
||||
|---|---|---|---|---|---|---|
| X1 | X2 | X3 | Y1c | Y2c | Y3c | |
| 1 | 1.00 | 0.00 | 0.00 | 26.7 ± 0.5 | 33.3 ± 1.4 | 22.3 ± 0.5 |
| 2 | 0.00 | 1.00 | 0.00 | 47.3 ± 0.1 | 2.2 ± 0.7 | 0.8 ± 0.2 |
| 3 | 0.00 | 0.00 | 1.00 | 56.6 ± 1.1 | 3.8 ± 0.5 | 1.0 ± 0.3 |
| 4 | 0.50 | 0.50 | 0.00 | 33.5 ± 0.1 | 21.8 ± 1.2 | 8.7 ± 1.1 |
| 5 | 0.50 | 0.00 | 0.50 | 30.3 ± 0.1 | 9.6 ± 0.4 | 4.4 ± 0.6 |
| 6 | 0.00 | 0.50 | 0.50 | 51.7 ± 0.4 | 2.4 ± 0.6 | 0.7 ± 0.1 |
| 7 | 0.33 | 0.33 | 0.33 | 35.4 ± 0.1 | 2.9 ± 0.7 | 1.4 ± 0.4 |
| 8 | 0.67 | 0.17 | 0.17 | 28.5 ± 0.1 | 25.2 ± 1.1 | 11.8 ± 0.3 |
| 9 | 0.17 | 0.67 | 0.17 | 41.8 ± 0.2 | 1.2 ± 0.4 | 0.8 ± 0.2 |
| 10 | 0.17 | 0.17 | 0.67 | 44.0 ± 0.6 | 1.0 ± 0.2 | 1.4 ± 0.5 |
a
Independent variables: X1, Rhodiola crenulata; X2, Panax quinquefolius; X3, Astragalus membranaceus.
b
Response variables: Y1, extraction yield; Y2, the percentage of NO production in the LPS-induced control; Y3, the percentage of IL-6 production in the LPS-induced control
c
All values are mean ± SD of triplicate determinations.