Table 3.
Recent licensed protein and DNA vaccine therapies (data extracted from 2001 to 2017; some of which are not related to infectious diseases).
|
Human | |||||
|---|---|---|---|---|---|
| Vaccine Type | Vaccine Target | Product Name | Administration | Date of Approval | Company involved |
| Live attenuated vaccine | Cholera | Vaxchora® | Oral | 2016 | PaxVax |
| Influenza | FluMist® | Intranasal | 2003 | MedImmune | |
| Inactivated vaccine | Influenza virus subtypes A and type B | Flucelvax® | Intramuscular | 2012 | Novartis |
| Influenza | Fluzone® | Intradermal | 2002 | Sanofi Pasteur | |
| Inactivated hepatitis A and recombinant protein | Hepatitis A and B | Twinrix® | Intramuscular | 2001 | GlaxoSmithKline |
| Toxoid conjugated vaccine | Invasive meningococcal disease | Menveo® | Intramuscular | 2010 | Novartis |
| Haemophilus influenzae type b | Hiberix® | Intramuscular | 2009 | GlaxoSmithKline | |
| Diphtheria, Tetanus, Acellular Pertussis, Hepatitis B, Polio | Pediarix® | Intramuscular | 2002 | GlaxoSmithKline | |
| Polysaccharide vaccine | Streptococcus pneumoniae | Prevnar 13® | Intramuscular | 2010 | Wyeth |
| Recombinant proteins | Meningococcal Group B | Bexsero® | Intramuscular | 2015 | Novartis |
| Influenza virus subtypes A and type B | Flublok® | Intramuscular | 2013 | Protein Science | |
| Animal | |||||
| DNA vaccine | West Nile virus | West Nile-Innovator® | Horses | 2005 | Fort Dodge |
| Infectious haematopoietic necrosis virus (IHNV) | Apex-IHN® | Salmon | 2005 | Novartis | |
| Growth hormone releasing hormone (GHRH) | LifeTide® SW5 | Swine | 2008 | VGX™ Animal Health | |
| Melanoma | Oncept™ | Dogs | 2010 | Merial | |