Table 1.
Annual consumption of several antimicrobial agents at the National Taiwan University Hospital, 2000–2010
| Antimicrobial consumption (DDD/1000 patient-days) by year |
Trend analysis |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Year | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | r | p |
| Vancomycin | 19.7 | 19.9 | 23.2 | 26.1 | 24.5 | 21.7 | 20.1 | 19.1 | 20.9 | 18.1 | 17.8 | 0.477 | 0.138 |
| Teicoplanin | 7.7 | 11.8 | 9.1 | 10.0 | 11.9 | 7.9 | 9.0 | 10.1 | 11.7 | 13.1 | 14.5 | 0.619 | 0.042* |
| Glycopeptidesa | 27.4 | 31.6 | 32.3 | 36.1 | 36.5 | 29.6 | 29.1 | 29.2 | 32.6 | 31.2 | 32.3 | 0.027 | 0.938 |
| Linezolid | 0.0 | 0.0 | 0.2 | 1.2 | 3.0 | 3.1 | 2.9 | 2.6 | 3.3 | 3.9 | 3.1 | 0.775 | 0.014* |
| Fusidic acid | 0.0 | 0.0 | 3.8 | 6.0 | 5.5 | 4.1 | 3.6 | 4.9 | 4.8 | 2.7 | 3.0 | 0.57 | 0.109 |
| Tigecycline | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.8 | 3.7 | 5.0 | 6.0 | 0.847 | 0.153 |
| Daptomycin | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.2 | 3.0 | — | — |
*Statistically significant association (p < 0.05).
DDD = defined daily dose.
a
Includes vancomycin and teicoplanin.