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. 2020 Jan 16;15(1):4–17. doi: 10.5469/neuroint.2019.00213

Table 3.

Summary of outcomes by agents

Bleomycin
Ethanol
Sodium tetradecyl sulfate
Ethanolamine
Pingamycin
% (95% CI) P-value vs. bleomycin % (95% CI) P-value vs. bleomycin % (95% CI) P-value vs. bleomycin % (95% CI) P-value vs. bleomycin % (95% CI) P-value vs. bleomycin
Complete cure 66.1 (31.3–100.9) Ref. 58.8 (39.8–77.9) 0.004 55.5 (36.1–74.9 ) 0.005 78.3 (58.9–97.6) <0.001 85.9 (72.7–99.2) <0.001
Partial cure 24.5 (1.7–47.3) Ref. 35.3 (19.1–51.5) 0.18 25.9 (13.1–38.6) 0.08 19.5 (2.1–37.0) 0.05 12.5 (1.0–24.0) 0.03
No benefit 12.9 (0.7–26.6) Ref. 4.0 (1.2–6.8) 0.003 14.9 (4.3–25.4) 0.02 2.1 (0.2–4.4) <0.001 2.6 (0.1–5.2) <0.001
Improvement in QoL Ref. 89.8 (76.4–3.2) 46.7 (22.4–71.0) 98.1 (94.5–100)
Patient satisfaction 94.3 (88.3–100.3) Ref. 96.0 (92.5–99.6) 0.72 72.8 (63.6–81.9) <0.001 76.5 (62.2–90.7) 0.02
Pulmonary complication 2.2 (0.0–5.4) Ref. 1.5 (0.2–2.8) 1.00 2.4 (0.5–5.3) 0.38 2.0 (0.0–5.9) 1.00 0.8 (0.0–2.3) 1.00
Skin necrosis/scar 2.3 (1.0–5.7) Ref. 1.4 (0.1–2.7) 0.69 2.1 (0.8–3.4) 0.71 2.0 (0.0–5.9) 1.00 0.8 (0.0–2.3) 0.35
Any permanent morbidity/mortality 2.2 (0.0–5.4) Ref. 1.0 (0.1–2.1) 1.00 0.5 (0.1–1.2) 1.00 1.8 (0.0–4.8) 1.00 0.8 (0.0–2.3) 1.00
Local temporary complication 27.0 (5.4–59.4) Ref. 30.0 (3.3–56.7) 0.61 44.0 (10.6–77.4) <0.001 51.0 (24.7–26.6) <0.001 36.2 (19.7–92.1) 0.45

CI, confidence interval; Ref., reference; QoL, quality of life.