Table 3.
Bleomycin |
Ethanol |
Sodium tetradecyl sulfate |
Ethanolamine |
Pingamycin |
||||||
---|---|---|---|---|---|---|---|---|---|---|
% (95% CI) | P-value vs. bleomycin | % (95% CI) | P-value vs. bleomycin | % (95% CI) | P-value vs. bleomycin | % (95% CI) | P-value vs. bleomycin | % (95% CI) | P-value vs. bleomycin | |
Complete cure | 66.1 (31.3–100.9) | Ref. | 58.8 (39.8–77.9) | 0.004 | 55.5 (36.1–74.9 ) | 0.005 | 78.3 (58.9–97.6) | <0.001 | 85.9 (72.7–99.2) | <0.001 |
Partial cure | 24.5 (1.7–47.3) | Ref. | 35.3 (19.1–51.5) | 0.18 | 25.9 (13.1–38.6) | 0.08 | 19.5 (2.1–37.0) | 0.05 | 12.5 (1.0–24.0) | 0.03 |
No benefit | 12.9 (0.7–26.6) | Ref. | 4.0 (1.2–6.8) | 0.003 | 14.9 (4.3–25.4) | 0.02 | 2.1 (0.2–4.4) | <0.001 | 2.6 (0.1–5.2) | <0.001 |
Improvement in QoL | Ref. | 89.8 (76.4–3.2) | 46.7 (22.4–71.0) | 98.1 (94.5–100) | ||||||
Patient satisfaction | 94.3 (88.3–100.3) | Ref. | 96.0 (92.5–99.6) | 0.72 | 72.8 (63.6–81.9) | <0.001 | 76.5 (62.2–90.7) | 0.02 | ||
Pulmonary complication | 2.2 (0.0–5.4) | Ref. | 1.5 (0.2–2.8) | 1.00 | 2.4 (0.5–5.3) | 0.38 | 2.0 (0.0–5.9) | 1.00 | 0.8 (0.0–2.3) | 1.00 |
Skin necrosis/scar | 2.3 (1.0–5.7) | Ref. | 1.4 (0.1–2.7) | 0.69 | 2.1 (0.8–3.4) | 0.71 | 2.0 (0.0–5.9) | 1.00 | 0.8 (0.0–2.3) | 0.35 |
Any permanent morbidity/mortality | 2.2 (0.0–5.4) | Ref. | 1.0 (0.1–2.1) | 1.00 | 0.5 (0.1–1.2) | 1.00 | 1.8 (0.0–4.8) | 1.00 | 0.8 (0.0–2.3) | 1.00 |
Local temporary complication | 27.0 (5.4–59.4) | Ref. | 30.0 (3.3–56.7) | 0.61 | 44.0 (10.6–77.4) | <0.001 | 51.0 (24.7–26.6) | <0.001 | 36.2 (19.7–92.1) | 0.45 |
CI, confidence interval; Ref., reference; QoL, quality of life.