Figure 3. Roscovitine increases ATRA-induced nuclear expression of Vav1.

(A) Western blots of nuclear lysate shows that ATRA enhances the relative expression of nuclear Vav1 compared to untreated cells and ATRA/roscovitine treated HL-60 cells further increases the level of Vav1 compared to ATRA alone at 72 h. (B) TATA binding protein (TBP) was the loading control. All blots shown are representative of three replicates.