Figure 4. Expression of adaptor proteins (c-Cbl, SLP-76) in the nucleus is enhanced by ATRA and roscovitine.

(A, B) Western blots of nuclear lysate show that ATRA enhances the expression of c-Cbl and SLP-76 compared to untreated cells and co-treatment with ATRA and roscovitine further increased their expression compared to ATRA alone at 72 h. (C). (B) TATA binding protein (TBP) was the loading control. All blots shown are representative of three replicates.