Figure 5. Roscovitine enhances ATRA-induced nuclear enrichment of IRF-1.

(A) Western blots of nuclear lysate show that ATRA enhances the relative expression of IRF-1 compared to untreated cells and cells co-treated with ATRA plus roscovitine further increases the level of IRF-1 compared to ATRA alone at 72 h. (B) TATA binding protein (TBP) was the loading control. All blots shown are representative of three replicates.