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. 2019 Oct 29;105(4):e1419–e1439. doi: 10.1210/clinem/dgz117

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Published by Oxford University Press on behalf of the Endocrine Society 2019.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 4. — Epithelial functions during implantation and protein regulation of epithelial regulators IRF8 and MEF2C. (A) Comparison of DEGs derived from the epithelium to DEGs derived from the whole endometrium, with a total of 658 genes that were uniquely regulated in the epithelium. (B–C) Immunohistochemistry staining for IRF8 (B) and MEF2C (C) in human endometrial samples during P and MS. Results show that both proteins were expressed in both the epithelium, with increased levels of IRF8 and increased cytoplasmic-nuclear translocation of MEF2C during the MS phase. Experiment was conducted on three independent patients’ samples and a representative is shown, alongside the negative control stained with secondary antibody only.