Fig. 6:

Q175 mice exhibited low HRV in the high frequency band. HRV measures were separated into high frequency (HF, 0.15–0.4 Hz) and low frequency (LF, 0.04–0.15 Hz) and bands, which are commonly used to quantify sympathetic and parasympathetic regulation, respectively. All genotypes exhibited subjective day/night differences in both frequency bands, The power of the HF band was disrupted with the middle-aged Hom Q175 (A) whereas the LF domain was unaltered (B). Individual data points are shown with WT (black circle, n=6), Het Q175 (grey triangle, n=10) and Hom Q175 (red diamonds, n=9).