Skip to main content
. Author manuscript; available in PMC: 2020 Mar 30.
Published in final edited form as: J Neurosci Res. 2018 Aug 31;96(12):1862–1875. doi: 10.1002/jnr.24320

Fig. 3:

Fig. 3:

Direct current injection or NMDA treatment rescues depressed daytime SFR of BACHD dSCN neurons. (A) Traces illustrating that positive current injection (5 or 10pA) increases the SFR of BACHD dSCN neurons during the day. (B) Summary of SFR and (C) Vm responses to current injection for WT (white bars and circles, n = 7) and BACHD (grey bars and white triangles, n = 12) neurons. (D) Example trace of BACHD dSCN neuron response to NMDA treatment (25 μM, 5 min). (E) Summary of NMDA SFR responses for WT (white circles, n = 11) and BACHD cells (white triangles, day, n =11). Bars are mean ± SEM. Two-way ANOVA with genotype and treatment as factors. Data were analyzed using a two-way ANOVA with genotype and treatment as factors. * = significant difference between genotypes; # = significant difference between treated and control.