BACHD SCN displayed increased expression of the alpha BK subunit. Kcnma1 expression was modestly higher in the mutant SCN. Gene expression levels of the BK subunits Kcnma1 (A), Kcnmb2 (B), Kcnmb4 (C) were analyzed in WT and BACHD SCN tissue by QPCR, normalized to the geometric mean of the housekeeping genes: Ppia and Rplp0, and are reported as the mean ± SEM of WT (n=6) and BACHD (n=7). When normalized one to the other, the expression levels of Ppia (WT: 0.8440 ± 0.05567; BACHD: 0.8178 ± 0.02205) or Rplp0 (WT: 1.208 ± 0.07056; BACHD: 1.228 ± 0.03333) did not differ between genotypes. * = significant difference between genotypes, t-tests.