Table VI. Subgroup analysis of per-protocol analysis.
| Parameter | Caesarean section n (%) n = 290 | Vaginal delivery n (%) n = 902 | OR (CI 95%) | P value | Adjusted OR (CI 95%) | P value |
|---|---|---|---|---|---|---|
| Primary outcomes | ||||||
| - Live birth | 51/276 (18.5) | 219/860 (25.5) | 0.66 (0.47–0.93) | .018 | 0.69 (0.48–0.98) | .041 |
| Secondary outcomes | ||||||
| - Clinical pregnancy | 86 (29.7) | 332 (36.8) | 0.72 (0.54–0.96) | .027 | 0.75 (0.57–1.03) | .080 |
| - Ongoing pregnancy | 67 (23.1) | 276 (30.6) | 0.68 (0.50–0.93) | .015 | 0.71 (0.53–0.99) | .004 |
| - No pregnancy | 169 (58.3) | 455 (50.4) | 1.37 (1.05–1.79) | .020 | 1.34 (1.02–1.78) | .051 |
| - Ectopic pregnancy | 0 | 0 | ||||
| - Mean implantation rate | 0.28 ± 0.45 | 0.35 ± 0.47 | 0.64 (0.46–0.91) | 0.03 | 0.66 (0.47–0.99) | .024 |
Logistic regression and multivariate regression analysis (adjusted for (1) age, (2) BMI, (3) smoking, (4) pervious fertility treatment, (5) indication for current fertility treatment (tubal, male factor or endometriosis) and for two effect-modifying factors being (1) embryo quality and (2) endometrial thickness)