Table 1.
DNA polymerasea |
Terminasea |
|||||
---|---|---|---|---|---|---|
Acyclovir | Penciclovir | Ganciclovir | Cidofovir | Foscavir | Letermovir | |
HSV-1 (HHV-1) | choice | approved | resistance | resistance | ||
HSV-2 (HHV-2)rowhead | choice | approved | resistance | resistance | ||
VZV (HHV-3) | choice | approved | resistance | resistance | ||
EBV (HHV-4) | off-label | off-label | off-label | |||
HCMV (HHV-5) | choice | approved | approved | approvedb | ||
HHV-6A | off-label | off-label | off-label | |||
HHV-6B | off-label | off-label | off-label | |||
HHV-7 | off-label | off-label | off-label | |||
HSHV (HHV-8) | off-label | off-label | off-label |
Drug target.
Approved for prophylaxis.